Cameron Diaz
as Amanda Woods

Kate Winslet
as Iris Simpkins

Jude Law
as Graham Simpkins

Jack Black
as Miles Dumont

Eli Wallach
as Arthur Abbott

Edward Burns
as Ethan

Rufus Sewell
as Jasper Bloom

Miffy Englefield
as Sophie

Emma Pritchard
as Olivia

Sarah Parish
as Hannah

Shannyn Sossamon
as Maggie

Bill Macy
as Ernie

Shelley Berman
as Norman

Kathryn Hahn
as Bristol

John Krasinski
as Ben

Alex O'Loughlin
as Kissing Couple

Odette Annable
as Kissing Couple

Bundle Williams
as Girl in Pub

Suzanne Dizon
as Newspaper Party Guest

Terry Diab
as Night Editor

Kenneth Danziger
as Editor

Hope Riley
as Sarah Smith-Alcott

Gilbert Esquivel
as Gardener

Steven Bruns
as Couple on Plane

Nikki Novak
as Couple on Plane

Judith Drake
as Woman on Plane

Pamela Dunlap
as Woman on Plane

Hal Douglas
as Movie Trailer Narrator (voice)

Jay Simpson
as Limo-Driver

Siobhan Pestano
as Couple with Dog

Charles Dinsdale
as Couple with Dog

Sarah Flind
as Market Clerk

Darline Ann Harris
as Arthur's Nurse

Marcell Brown
as Airport Security

Marina Morgan
as Graham's Friend

Lynden Edwards
as Graham's Friend

Lydia Blanco Garza
as Marta

Jon Prescott
as Maggie's Boyfriend

Patrick Cavanaugh
as Young Man at WGA

Justin Collins
as Young Man at WGA

James Franco
as James Franco (uncredited)

Lindsay Lohan
as Lindsay Lohan (uncredited)

Dustin Hoffman
as Dustin Hoffman (uncredited)

Dani Lennon
as Model (uncredited)

Steven Quale
as News Reporter (uncredited)

Lasco Atkins
as Embankment Pedestrian (uncredited)

Patrizia Barretto
as Traveler (uncredited)

Drew Bayers
as Man in Airport (uncredited)

Brad Carr
as Jakob Ethridge - Airport Passenger (uncredited)

Freddie De Grate
as Coach Passenger (uncredited)

Nicholas Downs
as Peter (uncredited)

Amber Elizabeth
as Shop Customer (uncredited)

Andy Gates
as Man on Tube (uncredited)

Elizabeth Hara
as Girl in Restaurant (uncredited)

Jake Head
as Mixer (uncredited)

Halbert Hernandez
as Man in Resturant (uncredited)

Steve Humphreys
as Jeffrey (uncredited)

Charles Kellam
as Man in Airport (uncredited)

Samantha Kelly
as Mrs. Ames - Schultz's Friend (uncredited)

Lucy Lewendon
as Passerby (uncredited)

Jamie McCall
as Party Guest (uncredited)

Mark A. Nash
as Newsroom (uncredited)

Ian Novotny
as WGA Man (uncredited)

Vanessa Ross
as Lindsay Lohan's Friend (uncredited)

Scott Slifer
as Passenger (uncredited)

David Venafro
as Usher (uncredited)

Leanne Wilson
as Girl in Bar (uncredited)