Jim Henson
as Kermit the Frog / Rowlf / Dr. Teeth / Waldorf / Doc Hopper's Men / Link Hogthrob / Swedish Chef (voice)

Frank Oz
as Miss Piggy / Fozzie Bear / Animal / Sam the Eagle / Doc Hopper's Men / Marvin Suggs / Swedish Chef (hands) / Motorcycle Guy (voice)

Jerry Nelson
as Floyd Pepper / Robin the Frog / Crazy Harry / Lew Zealand / Camilla / Dr. Bunsen Honeydew (assistant) (voice)

Richard Hunt
as Scooter / Statler / Janice / Sweetums / Beaker / Fozzie Bear (assistant) (voice)

Dave Goelz
as The Great Gonzo / Dr. Bunsen Honeydew / Zoot / Doglion / Iraqian in El Sleezo Cafe / Pig (voice)

Charles Durning
as Doc Hopper

Austin Pendleton
as Max

Edgar Bergen
as Himself / Charlie McCarthy (voice)

Milton Berle
as Mad Man Mooney

Mel Brooks
as Professor Max Krassman

James Coburn
as El Sleezo Cafe Owner

Dom DeLuise
as Bernie the Agent

Elliott Gould
as Beauty Contest Compere

Bob Hope
as Ice Cream Vendor

Madeline Kahn
as El Sleezo Patron

Carol Kane
as "Myth"

Cloris Leachman
as Lord's Secretary

Steve Martin
as Insolent Waiter

Richard Pryor
as Balloon Vendor

Telly Savalas
as El Sleazo Tough

Orson Welles
as Lew Lord

Paul Williams
as El Sleazo Pianist

Scott Walker
as Snake Walker

Lawrence Gabriel Jr.
as Sailor

Ira F. Grubman
as Bartender

H.B. Haggerty
as Lumberjack

Bruce Kirby
as Gate Guard

Tommy Madden
as One-Eyed Midget

James Frawley
as El Sleezo Cafe Waiter

Arnold Roberts
as Cowboy

Steve Whitmire
as Fletcher Bird / Scooter (assistant) (voice)

Kathryn Mullen
as Camilla (assistant)

Bob Payne
as Additional Muppet Performer

Eren Ozker
as Additional Muppet Performer

Caroly Wilcox
as Additional Muppet Performer

Olga Felgemacher
as Additional Muppet Performer

Bruce Schwartz
as Additional Muppet Performer

Michael Earl
as Animal (assistant) / Beaker (assistant) / Big Bird (assistant) / Dr. Teeth (assistant) / Fozzie Bear (assistant) / Janice (assistant) / Scooter (assistant)

Buz Suraci
as Additional Muppet Performer

Tony Basilicato
as Additional Muppet Performer

Adam Hunt
as Additional Muppet Performer

Caroll Spinney
as Big Bird (voice)

Fran Allison
as Additional Muppet Performer

Sherry Amott
as Additional Muppet Performer

Bil Baird
as Additional Muppet Performer

Peter Baird
as Additional Muppet Performer

Bob Baker
as Additional Muppet Performer

Cheryl Blaylock
as Additional Muppet Performer

Tim Burton
as Additional Muppet Performer

Bruce Chesse
as Additional Muppet Performer

Edward G. Christie
as Additional Muppet Performer

Melinda Dillon
as Woman with Balloon

Roy R. Etherington
as Additional Muppet Performer

Faz Fazakas
as Additional Muppet Performer

Wayland Flowers
as Additional Muppet Performer

Brian Froud
as Additional Muppet Performer

John Gilkerson
as Additional Muppet Performer

Brian Henson
as Additional Muppet Performer

Cheryl Henson
as Additional Muppet Performer

Heather Henson
as Additional Muppet Performer

Jane Henson
as Additional Muppet Performer

John Henson
as Additional Muppet Performer

Lisa Henson
as Additional Muppet Performer

Phillip Huber
as Additional Muppet Performer

Jerry Juhl
as Additional Muppet Performer

Frank Kane
as Additional Muppet Performer

Paul Kennemore
as Additional Muppet Performer

Earl Kress
as Additional Muppet Performer

John Landis
as Additional Muppet Performer

Ralph Lee
as Additional Muppet Performer

Shari Lewis
as Additional Muppet Performer

Kermit Love
as Additional Muppet Performer

John Lovelady
as Additional Muppet Performer

Mahlmann
as Additional Muppet Performer

Randal J. Metz
as Additional Muppet Performer

Wendy Midener
as Additional Muppet Performer

Frances Oznowicz
as Additional Muppet Performer

Isidore Oznowicz
as Additional Muppet Performer

Harry Sabin
as Additional Muppet Performer

Lettie Connell Schubert
as Additional Muppet Performer

Burr Tillstrom
as Additional Muppet Performer

Alice Tweedy
as Additional Muppet Performer

Curt Vig
as Additional Muppet Performer

Rik Vig
as Additional Muppet Performer

Rick Williamson
as Additional Muppet Performer

Paul Zaloom
as Additional Muppet Performer

Harry Sabin
as Additional Muppet Performer