Actor
Avatar 5
2031
as Kiri
Avatar 4
2029
as Kiri
The Mandalorian & Grogu
2026
Avatar: Fire and Ash
2025
as Kiri
The Gorge
2025
Master Gardener
2023
as Norma Haverhill
Avatar: The Way of Water
2022
as Kiri
Call Jane
2022
as Virginia
The Good House
2022
as Hildy Good
Ghostbusters: Afterlife
2021
as Dana Barrett
My Salinger Year
2020
as Margaret
Rakka
2017
as Jasper
The Meyerowitz Stories (New and Selected)
2017
as Sigourney Weaver
A Monster Calls
2016
as Grandma
Ghostbusters
2016
as Rebecca Gorin
Finding Dory
2016
as Sigourney Weaver (voice)
The Assignment
2016
as Dr. Rachel Kay
Chappie
2015
as Michelle Bradley
Exodus: Gods and Kings
2014
as Tuja
Vanya and Sonia and Masha and Spike
2012
as Masha
Vamps
2012
as Cisserus
The Cabin in the Woods
2012
as The Director
The Cold Light of Day
2012
as Jean Carrack
Red Lights
2012
as Margaret Matheson
Final Cut: Ladies and Gentlemen
2012
as (archive footage)
Rampart
2011
as Joan Confrey
Abduction
2011
as Dr. Geraldine 'Geri' Bennett
Paul
2011
as The Big Guy
Cedar Rapids
2011
as Macy Vanderhei
You Again
2010
as Ramona
Crazy on the Outside
2010
as Viki
Avatar
2009
as Dr. Grace Augustine
Prayers for Bobby
2009
as Mary Griffith
The Tale of Despereaux
2008
as The Narrator (voice)
WALL·E
2008
as Ship's Computer (voice)
Baby Mama
2008
as Chaffee Bicknell
Vantage Point
2008
as Rex Brooks
Be Kind Rewind
2008
as Ms. Lawson
The Girl in the Park
2007
as Julia Sandburg
The TV Set
2007
as Lenny
Happily N'Ever After
2007
as Frieda (voice)
Infamous
2006
as Babe Paley
Snow Cake
2006
as Linda
Imaginary Heroes
2004
as Sandy Travis
The Village
2004
as Alice Hunt
Holes
2003
as Louise Walker the Warden
The Guys
2002
as Joan
Tadpole
2002
as Eve Grubman
Big Bad Love
2001
as Betti DeLoreo (voice)
Through These Eyes
2001
as Narrator
Heartbreakers
2001
as Max Conners
Company Man
2000
as Daisy Quimp
Galaxy Quest
1999
as Gwen DeMarco
A Map of the World
1999
as Alice Goodwin
Alien Resurrection
1997
as Ripley
Snow White: A Tale of Terror
1997
as Lady Claudia Hoffman
The Ice Storm
1997
as Janey Carver
Copycat
1995
as Helen Hudson
Jeffrey
1995
as Debra Moorhouse
Death and the Maiden
1994
as Paulina Escobar
The Wild Swans
1994
as Narrator
Dave
1993
as Ellen Mitchell
Rabbit Ears - Peachboy
1993
as Narrator (voice)
The Snow Queen
1992
as Narrator (voice)
1492: Conquest of Paradise
1992
as Queen Isabella
Alien³
1992
as Ripley
Ghostbusters II
1989
as Dana Barrett
Working Girl
1988
as Katharine Parker
Gorillas in the Mist
1988
as Dian Fossey
Half Moon Street
1986
as Dr. Lauren Slaughter
Aliens
1986
as Ripley
One Woman or Two
1985
as Jessica Fitzgerald
Ghostbusters
1984
as Dana Barrett
Deal of the Century
1983
as Mrs. DeVoto
The Year of Living Dangerously
1982
as Jill Bryant
Eyewitness
1981
as Tony Sokolow
O Youth and Beauty!
1979
as Marcia Lawton
The Sorrows of Gin
1979
as Marcia Lawton
Alien
1979
as Ripley
Madman
1978
as Gale
Annie Hall
1977
as Alvy's Date Outside Theatre
Dust Bunny