Mckenna Grace
as Phoebe Spengler

Paul Rudd
as Gary Grooberson

Carrie Coon
as Callie Spengler

Finn Wolfhard
as Trevor Spengler

Dan Aykroyd
as Ray Stantz

Kumail Nanjiani
as Nadeem Razmaadi

Patton Oswalt
as Dr. Hubert Wartzki

Celeste O'Connor
as Lucky Domingo

Logan Kim
as Podcast

Emily Alyn Lind
as Melody

James Acaster
as Lars Pinfield

Bill Murray
as Peter Venkman

Ernie Hudson
as Winston Zeddemore

Annie Potts
as Janine Melnitz

William Atherton
as Mayor Walter Peck

Shelley Williams
as Senior Advisor

Chris Tummings
as Police Chief

John Rothman
as Library Administrator

Stephen Whitfield
as Fire Captain (1904)

Samuel Greco
as Firefighter (1904)

Chris Ginesi
as Firefighter (1904)

Brandon Burke
as Firefighter (1904)

Karack Osborn
as Firefighter (1904)

Kevin Mangold
as Slimer (Puppeteer)

Ian Whyte
as Garraka (Puppeteer)

Natalie Cousteau
as Dadi

Allison McKay
as Ms. Mikowski

Adam Speers
as Doll Owner

Claire Titelman
as News Correspondent

Kalisha Amaris Johnson
as Reporter

Evelyn Edwards
as Reporter

Andrew Goddard
as Reporter

Deeivya Meir
as Reporter

Sophia Lucia Parola
as Woman (Beach)

Megan Robinson
as Mother (Coffee Shop)

Evelyn Anne Bulls
as Child (Coffee Shop)

Camari Brown
as Man Running Away (Beach)

Claudia Nell McCoy
as Woman Running Away (Beach)

Damian Muziani
as Taxi Driver (In Traffic)

Remy Germinario
as Tourist Couple Looking at Map

Michael Kushner
as Tourist Couple Looking at Map

Deisy Patiño
as Woman's Friend at Beach

Victoria Giler
as Woman's Friend at Beach

Cassidy Goron
as Child (Beach)

Georgia Arron
as Podcast's Fan

Jesse Gallegos
as Vape Shop Clerk

Jonathan Mercedes
as NY Cop

Vinnie Coppola
as NY Cop

A.J. Voliton
as NYC Bystander

Adam Murray
as Truck Driver

Pat Kiernan
as News Anchor

Shelby Young
as Mini-Pufts (voice) (uncredited)

Ryan Bartley
as Mini-Pufts (voice) (uncredited)

Bella Glanville
as Influencer (uncredited)