Harrison Ford
as Richard Kimble

Tommy Lee Jones
as Samuel Gerard

Joe Pantoliano
as Cosmo Renfro

Jeroen Krabbé
as Charles Nichols

Daniel Roebuck
as Biggs

L. Scott Caldwell
as Poole

Tom Wood
as Newman

Ron Dean
as Detective Kelly

Joseph F. Kosala
as Detective Rosetti

Andreas Katsulas
as Frederick Sykes

Sela Ward
as Helen Kimble

Julianne Moore
as Anne Eastman

Miguel Nino
as Chicago Cop #1

John Drummond
as Newscaster

Tony Fosco
as Chicago Cop #2

Joseph F. Fisher
as Otto Sloan

James Liautaud
as Paul

David Darlow
as Dr. Lentz

Tom Galouzis
as Surgeon

James F. McKinsey
as Surgeon

Mark D. Espinoza
as Resident

John E. Ellis
as Anesthesiologist

Gene Barge
as 11th District Cop

Thomas Charles Simmons
as 11th District Cop

Joe Guzaldo
as Prosecutor

Dick Cusack
as Walter Gutherie

Nicholas Kusenko
as Assistant Defense Attorney

Joan Kohn
as Assistant Prosecuting Attorney

Joe Guastaferro
as Coroner

Andy Romano
as Judge Bennett

Richard Riehle
as Old Guard

Thom Vernon
as Carlson

Ken Moreno
as Partida

Eddie Bo Smith Jr.
as Copeland

Frank Ray Perilli
as Jail Officer

Otis Wilson
as Jail Officer

Pancho Demmings
as Young Guard

Jim Wilkey
as Bus Driver

Danny Goldring
as Head Illinois State Trooper

Nick Searcy
as Sheriff Rawlins

Kevin Crowley
as State Trooper

Michael James
as Head Welder

Michael Skewes
as Highway Patrolman

Ila Cathleen Stallings
as Duty Nurse

Linda Casaletto
as Rural Hospital Nurse

Cody Glenn
as Paramedic

Cynthia Baker
as Woman in Car

Johnny Lee Davenport
as Marshal Henry

Mike Bacarella
as Marshal Stevens

Bill Cusack
as Tracing Technician

David U. Hodges
as Marshal David

Lillie Richardson
as Copeland's Girlfriend

Peter J. Caria IV
as Billy

Tighe Barry
as Windshield Washer

Monika Chabrowski
as Polish Landlady

Lonnie Sima
as Landlady's Son

Oksana Fedunyszyn
as Myoelectric Receptionist

Orlando García
as Desmondo

Afram Bill Williams
as Salesman

Bruce L. Gewertz
as Dr. Bruce

Jane Lynch
as Kathy Wahlund

Joseph Rotkvich
as Officer Joseph

Steven Lilovich
as Officer Steve

Noelle Bou-Sliman
as Myoelectric Technician

Roxanne Roberts
as Trauma Doctor

Alex P. Hernandez
as Trauma Doctor

Theron Touché Lykes
as Orderly

Joel Robinson
as Boy Patient

Greg Hollimon
as Skating Orderly

Cheryl Lynn Bruce
as O.R. Doctor

Marie Ware
as Nurse Gladys

Bernard McGee
as Man

Ann Whitney
as Myoelectric Director

Lily Monkus
as Desk Clerk

Willie Lucas
as Desk Clerk

Turk Muller
as Clearing Officer

Ana María Alvarez
as La Cubana

Eugene F. Crededio
as Visitation Guard

Maurice Person
as Clive Driscoll

Terry Hard
as Officer Hormel

Pam Zekman
as Newscaster

David Pasquesi
as Newscaster

Brent Shaphren
as Doctor at Bar

Stephen A. Landsman
as Doctor at Bar

B.J. Jones
as Doctor at Bar

Dru Anne Carlson
as Gerard's Secretary

Margaret Moore
as Nichols' Assistant

Manny Lopez
as Seminar Doctor

John M. Watson Sr.
as Bones Roosevelt

Kirsten Nelson
as Betty

Juan Ramírez
as Man on 'El'

Neil Flynn
as Transit Cop

Allen Hamilton
as Host

Eric Fudala
as Hotel Security Guard

Lester Holt
as Newscaster

Jay Levine
as Newscaster

Sal Richards
as Warrant Captain (uncredited)

Darren W. Conrad
as Deputy at Train Wreck (uncredited)

Kevin Mukherji
as Doctor (uncredited)

John-Clay Scott
as Mad Motorist at Tunnel (uncredited)

Suzy Brack
as City Hall Employee (uncredited)

Gene Kelly
as US Marshall (uncredited)