Jacob Tremblay
as Luca Paguro (voice)

Jack Dylan Grazer
as Alberto Scorfano (voice)

Emma Berman
as Giulia Marcovaldo (voice)

Saverio Raimondo
as Ercole Visconti (voice)

Maya Rudolph
as Daniela Paguro (voice)

Marco Barricelli
as Massimo Marcovaldo (voice)

Jim Gaffigan
as Lorenzo Paguro (voice)

Peter Sohn
as Ciccio (voice)

Lorenzo Crisci
as Guido (voice)

Marina Massironi
as Signora Marsigliese (voice)

Gino La Monica
as Tomasso (Old Fisherman) (voice)

Sandy Martin
as Grandma Paguro (voice)

Giacomo Gianniotti
as Giacomo (Young Fisherman) (voice)

Elisa Gabrielli
as Concetta Aragosta (voice)

Mimi Maynard
as Pinuccia Aragosta (voice)

Sacha Baron Cohen
as Uncle Ugo (voice)

Francesca Fanti
as Maggiore (Cop) (voice)

Jonathan Nichols
as Priest (voice)

Enrico Casarosa
as Card Player / Angry Fisherman (voice)

Jim Pirri
as Mr. Branzino (voice)

Arturo Sorino
as Additional Voices (voice)