Taraji P. Henson
as Katherine G. Johnson

Octavia Spencer
as Dorothy Vaughan

Janelle Monáe
as Mary Jackson

Kevin Costner
as Al Harrison

Kirsten Dunst
as Vivian Mitchell

Jim Parsons
as Paul Stafford

Mahershala Ali
as Jim Johnson

Glen Powell
as John Glenn

Ariana Neal
as Joylette Johnson

Saniyya Sidney
as Constance Johnson

Zani Jones Mbayise
as Kathy Johnson

Donna Biscoe
as Joylette Coleman

Olek Krupa
as Karl Zielinski

Aldis Hodge
as Levi Jackson

Kimberly Quinn
as Ruth

Frank Hoyt Taylor
as Judge

Lidya Jewett
as Young Katherine

Karan Kendrick
as Younger Joylette

Jaiden Kaine
as Joshua Coleman

Kurt Krause
as Sam Turner

Ken Strunk
as Jim Webb

Selah Kimbro Jones
as Carolyn Marie Jackson

Tre Stokes
as Levi Jackson Jr.

Corey Mendell Parker
as Howard Vaughan

Ashton Tyler
as Leonard Vaughan

Alkoya Brunson
as Kenneth Vaughan

Ron Clinton Smith
as White Cop

Gregory Alan Williams
as Marion Smithson

Maria Howell
as Ms. Sumner

Arnell Powell
as Professor Graves

Crystal Lee Brown
as Bernie

Tequilla Whitfield
as Eleanor

Dane Davenport
as Alan Shepard

Evan Holtzman
as Deke Slayton

Travis Smith
as Scott Carpenter

Scott Michael Morgan
as Bill Calhoun

Chris Cavalier
as IBM Technician

Robert G. McKay
as Pastor Ayres

Rhoda Griffis
as White Librarian

Karen Wheeling Reynolds
as Court Clerk

Kate Kneeland
as Court Clerk

Joe Knezevich
as Wind Tunnel PA Announcer

Paul Ryden
as TV Reporter at Cape Canaveral

John Atwood
as Newscaster

Jon Edwin Wright
as Newscaster

Wilbur Fitzgerald
as Senator Patrick

Michael Hartson
as Night School Professor

Bob Jennings
as Navy Officer

Gary Weeks
as Reporter at Press Conference

Afemo Omilami
as Man Outside Store

Cullen Moss
as Mission Control Commander

Amy Tipton
as Woman Crying

Elijah Everett
as Man Crying

Andre Pushkin
as Russian Scientist

Randall Newsome
as Russian Scientist

Joe Hardy Jr.
as Gordon Cooper

Howie Johnson
as Library Security Guard

David Kallaway
as NASA Security Guard

Addison Rose Melfi
as Addie Marcus

Paige Nicollette
as Eunice (uncredited)