Matt Damon
as Paul Safranek

Christoph Waltz
as Dusan Mirkovic

Hong Chau
as Ngoc Lan Tran

Kristen Wiig
as Audrey Safranek

Rolf Lassgård
as Dr. Jorgen Asbjørnsen

Ingjerd Egeberg
as Anne-Helene Asbjørnsen

Udo Kier
as Konrad

Søren Pilmark
as Dr. Andreas Jacobsen

Jason Sudeikis
as Dave Johnson

Maribeth Monroe
as Carol Johnson

Jayne Houdyshell
as Paul's Mother

Phil Reeves
as Audrey's Dad Larry

James Van Der Beek
as Anesthesiologist

Alison J. Palmer
as Anesthesiologist's Wife

Tim Driscoll
as Good Friend Tim

Kristen Thomson
as Good Friend Gina

Kevin Kunkel
as Buddy Kevin

Patrick Gallagher
as Drunk Guy at Bar

Linda M. Anderson
as Realtor

John Reynolds
as Estate Sale Buyer

Carmen Orellana
as Meat Cutter Carmen

David Noonen
as Meat Cutter Dave

Bob Bezousek
as Omaha Steaks Bob

Ana Marie Cox
as TV Pundit

Roland Martin
as TV Pundit

Milo Goodman
as Mortgage Broker

Dave Sokolowski
as Friend at Bar

Michael Heathcote
as Carrying Box Carrier

Martha Girvin
as Curious Reunion Friend

Brendan Beiser
as Reunion Friend

Alison Brooks
as Reunion Friend

Paul Constable
as Reunion Friend

Neil Patrick Harris
as Jeff Lonowski

Laura Dern
as Laura Lonowski

Niecy Nash-Betts
as Leisureland Salesperson

Margo Martindale
as Woman on Shuttle

Kerri Kenney
as Single Mom Kristen

Donna Lynne Champlin
as Leisureland Administrator

Don Lake
as Leisureland Guide Matt

Mary Kay Place
as Land's End Customer (voice)

Sherry Mandujano
as Waiting Room Nurse

Kimberly Kodatsky
as Treatment Room Nurse

Larry Mannell
as Downsizing Supervisor

Kerry-Lee Finkle
as Downsizing Nurse

Natasha Bromfield
as Recovery Room Nurse

Raffaele Brereton
as Leisureland Orderly

Damiãn Garth Brown
as Leisureland Orderly

Jermaine Otis Granville
as Leisureland Orderly

Jeffrey Sinclair
as Leisureland Orderly

Richard D. Leko
as Woman on Shuttle's Son

Jon De Leon
as Keepsake Box Mover

Howard J. Davis
as Keepsake Box Mover

Maryam Moshiri
as BBC Anchor

Bill Coulter
as Brian Fakler

Jeff Clarke
as Divorce Lawyer

Juan Carlos Velis
as Call Center Co-Worker

Paul Mabon
as Olive Garden Roger

Veena Sood
as Leislureland Housewife

Nick Douzenis
as Greek Party Guest

Spiros Kontos
as Greek Party Guest

Maria Kontou
as Greek Party Guest

Peter Melatos
as Greek Party Guest

Loukia Papadapoulos
as Greek Party Guest

Paul Landais
as Spaniard

Rodrigo Salera
as Spaniard

Salvador Sindoni
as Spaniard

Balaram Vilchis
as Spaniard

Ann Bordwine Beeder
as Cool Woman at Dusan's Party

Kathryn Aboya
as Dose Girl at Dusan's Party

Brigette Lundy-Paine
as Dusan's Girlfriend

Kristina Cocoli
as Dusan's Party Girl

Lina Shekhovtsova
as Dusan's Party Girl

Jeffrey R. Smith
as Guy at Dusan's Party

Pepe Serna
as Señor Cárdenas

Rose Bianco
as Gladys

Lidia Perez
as Ringworm Mother

Ramon Marroquin
as Ringworm Father

Cicela Bravatti
as Bickering Deaf Couple

Jorge Tello
as Bickering Deaf Couple

Pamela Archer
as Alondra Resident

Dalila Gamboa Diaz
as Alondra Resident

Margareta Pettersson
as Solveig Edvardsen

Joaquim de Almeida
as Conference Director Dr. Pereira

Cameron Geddes
as Little Ronni

Bjørnar Egede-Nissen
as Torvald

Warren Belle
as Tunde

George B. Seremba
as Asbjørnsen's Colleague

Christoph Friedrich Richter
as Norway Colony Scientist

Michaela Sanielevici
as Norway Colony Scientist

Caroline Andersen
as Colony Member

Erik Andersen
as Colony Member

Solveig Barber
as Colony Member

Aaron Befus
as Colony Member

Bent Brakas
as Colony Member

Steve Fievet
as Colony Member

Jahkeil Goldson
as Colony Member

David Gudjonsson
as Colony Member

Marianne Haldorsen
as Colony Member

Jani Hamalainen
as Colony Member

Ida Linckert Hertzman
as Colony Member

Erik Irwin
as Colony Member

Anastasia Kharlamova
as Colony Member

Ksenia Daniela Kharlamova
as Colony Member

Aleksander Krogevoll
as Colony Member

Elizabeth Jeanne le Roux
as Colony Member

Tero Konttinen
as Colony Member

Raimo Kurppa
as Colony Member

Kristin Lyssand
as Colony Member

Mark Makivirta
as Colony Member

Sari Miettinen
as Colony Member

Tanya Missirlian
as Colony Member

Antti Muhunen
as Colony Member

Kent Nielsen
as Colony Member

Riita Nikolakakos
as Colony Member

Velva Nystrom
as Colony Member

Thomas Paloheimo
as Colony Member

Lars Paronen
as Colony Member

Jacob Pettersson
as Colony Member

Kimberly Rowntree
as Colony Member

Jorgen Runas
as Colony Member

Michael Skretteberg
as Colony Member

Tomas Straum
as Colony Member

Kari Svenneby
as Colony Member

Alari Tork
as Colony Member

Thomas Wicks
as Colony Member

Kristina Yedlitska
as Colony Member

Hélène Cardona
as Newscaster (uncredited)