Steve Martin
as Neal Page

John Candy
as Del Griffith

Laila Robins
as Susan Page

Michael McKean
as State Trooper

Dylan Baker
as Owen

Kevin Bacon
as Taxi Racer

Olivia Burnette
as Marti Page

Carol Bruce
as Joy Page

Diana Douglas
as Peg

Martin Ferrero
as Motel Clerk

Larry Hankin
as Doobie

Richard Herd
as Walt

Susan Kellermann
as Waitress

Matthew Lawrence
as Little Neal

Edie McClurg
as Car Rental Agent

Susan Isaacs
as Marie

John Randolph Jones
as Cab Dispatcher

Ben Stein
as Wichita Airport Rep

Lyman Ward
as John

George Petrie
as Martin

Gary Riley
as Motel Thief

Charles Tyner
as Gus

Lulie Newcomb
as Owen's Wife

Nicholas Wyman
as New York Lawyer

Gaetano Lisi
as Cab Driver - New York

Diana Castle
as Stewardess #1

Julie H. Morgan
as Stewardess #2

Bill Erwin
as Man on Plane

Ruth de Sosa
as New York Ticket Agent

Kim Genelle
as Receptionist

Grant Forsberg
as Brand Manager

David Raiport
as Cafe Patron

Andrew J. Hentz
as Bus Lover

Karen Meisinger
as Bus Loverette

Gary Palmer
as Pilot

John Moio
as Screaming Driver

Victoria Vanderkloot
as Screaming Driver's Wife

William Windom
as Mr. Bryant