Seth Rogen
as Mac Radner

Zac Efron
as Teddy Sanders

Rose Byrne
as Kelly Radner

Dave Franco
as Pete Regazolli

Christopher Mintz-Plasse
as Scoonie Schofield

Jerrod Carmichael
as Garf

Ike Barinholtz
as Jimmy Blevins

Carla Gallo
as Paula Faldt

Halston Sage
as Brooke Shy

Craig Roberts
as Assjuice

Lisa Kudrow
as Carol Gladstone

Elise Vargas
as Stella Radner

Zoey Vargas
as Stella Radner

Brian Huskey
as Bill Wazowkowski

Ali Cobrin
as Whitney

Kira Sternbach
as Brittany

Steven Michael Eich
as Thumbsucker

Andy Samberg
as Toga #1

Akiva Schaffer
as Toga #2

Jorma Taccone
as Toga #3

Adam Devine
as Beer Pong Guy #1

Blake Anderson
as Beer Pong Guy #2

Anders Holm
as Beer Pong Guy #3

Kyle Newacheck
as Beer Pong Guy #4

Jake Johnson
as Sebastian Cremmington

Hannibal Buress
as Officer Watkins

Liz Cackowski
as Wendy the Realtor

Jason Mantzoukas
as Dr. Theodorakis

Jesse Heiman
as The Babysitter

Randall Park
as Rep

Natasha Leggero
as Prostitute

Casey Ford Alexander
as Gay Couple (uncredited)

Michael Angeloe
as Birthday Party Jumper (uncredited)

Fahim Anwar
as Rival Frat Guy #1 (uncredited)

Melanie Avalon
as Sorority Girl (uncredited)

Chasty Ballesteros
as Alecia (uncredited)

Marianne Bourg
as Sorority Girl (uncredited)

Erika Del Toro
as Sorority Girl (uncredited)

Alanna Dergan
as Sorority Girl (uncredited)

Robert Dunne
as Pledge (uncredited)

Elsi Eng
as Sorority Girl (uncredited)

Ayesha Fraser
as Sorority Girl (uncredited)

Danika Galindo
as Sorority Girl (uncredited)

Ori Kalmus
as Rival Frat Guy #2 (uncredited)

Maria Olsen
as Prostitute (uncredited)

Gary Sievers
as Homeless Man (uncredited)

Stephen Todt
as JJ (uncredited)

Cassandra Starr
as Sorority Girl (uncredited)

Valeria Sweet
as Sorority Girl (uncredited)

Bridgetta Tomarchio
as Sorority Girl (uncredited)