Johnny Depp
as Raoul Duke

Benicio del Toro
as Dr. Gonzo

Tobey Maguire
as Hitchhiker

Michael Lee Gogin
as Uniformed Dwarf

Larry Cedar
as Car Rental Agent - Los Angeles

Brian Le Baron
as Parking Attendant

Katherine Helmond
as Desk Clerk at Mint Hotel

Michael Warwick
as Bell Boy

Craig Bierko
as Lacerda

Tyde Kierney
as Reporter

Mark Harmon
as Magazine Reporter

Tim Thomerson
as Hoodlum

Richard Riehle
as Dune Buggy Driver

Ransom Gates
as Dune Buggy Passenger

Frank Romano
as Dune Buggy Passenger

Gil Boccaccio
as Desert Room Doorman

Gary Bruno
as Desert Room Doorman

Richard Portnow
as Wine Colored Tuxedo

Debbie Reynolds
as Debbie Reynolds (voice)

Steve Schirripa
as Goon

Verne Troyer
as Wee Waiter

Will Blount
as The Black Guy

Ben Yeagar
as Clown Barker

Penn Jillette
as Carnie Talker

Christopher Callen
as Bazooko Circus Waitress

Cameron Diaz
as Blonde TV Reporter

Benjamin A. Van Der Veen
as TV Crew Man

Lyle Lovett
as Road Person

Flea
as Musician

Alex Craig Mann
as Stockbroker

Gregory Itzin
as Mint Hotel Clerk

Gary Busey
as Highway Patrolman

Troy Evans
as Police Chief

Gale Baker
as Police Chief's Wife

Christopher Meloni
as Clerk at Flamingo Hotel

Christina Ricci
as Lucy

Chris Hendrie
as Executive Director

Larry Brandenburg
as Cop in Car

Michael Jeter
as Ron Bumquist

Donald Morrow
as Film Narrator (voice)

Harry Dean Stanton
as Judge

Jenette Goldstein
as Maid

Stephen Bridgewater
as Human Cannonball

Buck Holland
as Shopper

Mary Gillis
as Shopper

Jennifer Elise Cox
as Shopper

Robert Allen
as Car Rental Agent - Los Angeles

David Brisbin
as Man in Car

Ellen Barkin
as Waitress at North Star Cafe

James O'Sullivan
as TV Newsman

Milt Tarver
as TV Newsman

Kathryn Alexander
as Lizard Performer

Mia Babalis
as Lizard Performer

Kristin Draudt
as Lizard Performer

Kim Flowers
as Lizard Performer

Trudi Forristal
as Lizard Performer

Nan Friedman
as Lizard Performer

Judith Lieff
as Lizard Performer

Tane McClure
as Lizard Performer

Diana Mehoudar
as Lizard Performer

Geoffrey Nimmer
as Lizard Performer

Marlene Bologna
as Trapeze Artist

Chobi Gyorgy
as Trapeze Artist

Karen Price
as Trapeze Artist

Lisa Hoyle
as Trapeze Artist

Joseph S. Griffo
as Trapeze Artist

Laraine Newman
as Frog-Eyed Woman (uncredited)

Hunter S. Thompson
as Other Duke in Matrix Flashback (uncredited)