Angela Bassett
as Anna Mae Bullock / Tina Turner

Laurence Fishburne
as Ike Turner

Vanessa Bell Calloway
as Jackie

Jenifer Lewis
as Zelma Bullock

Khandi Alexander
as Darlene

Richard T. Jones
as Ike Turner Jr.

Rae'Ven Larrymore Kelly
as Young Anna Mae Bullock

Chi McBride
as Fross

Penny Johnson Jerald
as Lorraine Taylor

Phyllis Yvonne Stickney
as Alline Bullock

Sherman Augustus
as Reggie

Cora Lee Day
as Grandma Georgiana

Virginia Capers
as Choir Mistress

Barry Shabaka Henley
as El Paso Doctor

Bo Kane
as Dance Show Host

Jackie O'Brien
as Boutique Clerk

Michael Colyar
as Apollo Announcer

Rob LaBelle
as Phil Spector

Patricia Sill
as Spector's Assistant

Shavar Ross
as Michael Turner

Damon Hines
as Ronnie Turner

Suli McCullough
as Craig Turner

Daniel McDonald
as London Announcer

O'Neal Compton
as George, Ramada Inn Manager

Rose Jackson
as 5th Ikette

Tina Turner
as Tina Turner (archive footage)

Gene 'Groove' Allen
as Club Announcer

Timmy Cappello
as Keyboards Player