Amy Adams
as Rose Lorkowski

Emily Blunt
as Norah Lorkowski

Steve Zahn
as Mac

Alan Arkin
as Joe Lorkowski

Clifton Collins Jr.
as Winston

Eric Christian Olsen
as Randy

Kevin Chapman
as Carl Swanson

Jason Spevack
as Oscar Lorkowski

Mary Lynn Rajskub
as Lynn

Paul Dooley
as Sherm

Judith Jones
as Paula Datzman-Mead

Amy Redford
as Heather

Susie Yip
as Mrs. Kim

Lois Geary
as Mrs. Davis

McKenna Hutton
as Young Rose

Mason Frank
as Young Norah

Amber Midthunder
as Candy Store Girl

Angelique Midthunder
as Girl's Mother

Vic Browder
as Gun Shop Owner

Ivan Brutsche
as Above and Beyond Worker

Kathy Lamkin
as Fair N Square Owner (uncredited)