Rick Moranis
as Wayne Szalinski

Marcia Strassman
as Diane Szalinski

Robert Oliveri
as Nick Szalinski

Daniel Shalikar
as Adam Szalinski

Joshua Shalikar
as Adam Szalinski

Lloyd Bridges
as Clifford Sterling

John Shea
as Hendrickson

Keri Russell
as Mandy

Ron Canada
as Marshall Brooks

Amy O'Neill
as Amy Szalinski

Michael Milhoan
as Capt. Ed Myerson

Gregory Sierra
as Terence Wheeler

Leslie Neale
as Constance Winters

Julia Sweeney
as Nosey Neighbor

Linda Carlson
as Nosey Neighbor

Lisa Mende
as Lab Technician

John Paragon
as Lab Technician

Kenneth Tobey
as Smitty

Bill Moseley
as Federal Marshall

Edward S. Feldman
as Las Vegas Couple

Suzanne Kent
as Las Vegas Couple

Alex Daniels
as Uncle Yanosh

Robert Jaffe
as Motorcycle Officer

Ron Lawrence
as Motorcycle Officer

John Hora
as Helicopter Observer

Mary Ellen Moore
as Police Woman

Randy Swallow
as Vegas Reporter

Pamela Cederquist
as Vegas Reporter

James M. Lauten
as Vegas Reporter

Shannon M. Steger
as Nevada Militia

Minori Goto
as Japanese Tourist

Mamoru Kanal
as Japanese Tourist

Gregory McCurdy
as Police Officer

David Scates
as Rock Fan in Crowd

Marion Palmer
as Hard Rock Reporter

Kathy Pastor
as Hard Rock Hostess

Bill Loska
as Highway Patrol Officer

Richard Simmons
as Self - (Archive Footage)